Rockefeller University Research Assistant, Neurobiology in New York, New York
Job Title Research Assistant, Neurobiology
Laboratory / Department Laboratory of Neurobiology
Our aim is to understand mechanisms of sensory processing in the cortex by working at the interface of microcircuitry, receptive field properties, and functional architecture, and to establish the relationship between the operation of neuronal ensembles and perceptual performance. We study the mechanisms of neural integration by exploring how the various sources of inputs to a cell interact to generate its functional properties. A key element in our studies of cortical microcircuitry was the discovery of a plexus of long-range horizontal connections in the cortex, which we now find mediate spatial integration and dynamic properties of cortex. We have studied the functional implications of these connections, exploring how cells responses are modulated by the context within which a stimulus is presented. These results fit with psychophysical studies demonstrating the dependence of perception on context, and lead to a novel view of cortical processing: Adult neurons, rather than having fixed functional properties, are dynamically tuned, changing their specificities with varying sensory experience. We have used these findings as a basis for making computational models relating the properties of neuronal ensembles to perceptual performance. These models enable us to understand how neurons, acting as an interactive ensemble, determine visual attributes in a manner that depends on the conjoint activity within the ensemble.
The Research Assistant will participate in a project involving the circuit mechanisms of visual processing in the mammalian brain. Responsibilities include assisting in animal surgery, viral injections, developing rodent operant boxes, training animals, data analysis, two-photon imaging, organizing laboratory, and purchasing supplies.
Bachelor's degree in science required. Must be comfortable working with mice and rats. Programming knowledge such as MatLab and Arduino is strongly desired.
The Rockefeller University is an Equal Opportunity Employer - Minorities/Women/Disabled/Veterans